George Kosana hails from Clairton, Pennsylvania to parents Stephen and Elizabeth. He has one older brother, also named Stephen. Though he has not married, he has living family throughout the country; three nieces, Lise (Prestine), Deborah (Kosana), and Kimberly (Bednarek). He has two great-nieces, Katherine (Prestine) and Anna (Bednarek), and one great-nephew, Robert (Bednarek).
George's most significant role was that of Sheriff McClelland in the 1968 original, Night of the Living Dead, directed by George A. Romero.